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Ownership Profile

Ownership Profile

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 48 38.91 65.44 46,472,127
Mutual Fund 23 2.27 4.97 3,530,584
Insider 10 0.88 1.80 1,275,708

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 17 1.29 2.05 1,459,151
Sellers 21 -1.89 2.89 -2,052,907
Net -0.60 0.84 -593,756

Concentration

Value ($MM) % O/S Shares
Total Inst. 39.78 67.24 47,747,835
Top 10 Inst. 33.80 57.36 40,730,368
Top 20 Inst. 38.43 64.70 45,942,455
Top 50 Inst. 39.78 67.24 47,744,214

Style

Holders Value ($MM) % Inst Shares Shares
Growth 5 0.63 0.99 701,362
Aggressive Growth 1 0.52 0.83 589,825
Core Growth 3 0.06 0.10 70,515
Growth 1 0.04 0.06 41,022
Income 2 0.02 0.04 27,010
Income Value 1 0.02 0.04 25,594
Yield 1 -- -- 1,416
Index 5 1.92 3.03 2,151,856
Other 21 27.14 45.95 32,629,762
Broker Dealer 3 1.18 1.86 1,324,029
GARP 4 0.06 0.18 127,182
Hedge Fund 11 16.17 25.58 18,164,358
Specialty -- --
VC Private Equity 3 9.73 18.33 13,014,193
Value 4 0.55 0.88 621,681
Core Value 1 0.04 0.06 43,569
Deep Value 3 0.51 0.81 578,112

Location: Global Region

Holders % O/S Shares Share Value
North America 56 62.31 44,247,742 37,269,747
Europe 2 4.93 3,500,093 2,513,433

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Stonepine Capital Management, LLC 6,439,498 9.07 -44,112 6/30/19
Avoro Capital Advisors LLC 6,240,000 8.79 -- 6/30/19
Deerfield Management Company, L.P. 6,052,935 8.52 -- 6/30/19
Armistice Capital LLC 5,836,000 8.22 -1,100,000 6/30/19
Domain Associates, L.L.C. 3,625,838 5.11 -- 9/13/19
HBM Partners AG 3,500,000 4.93 -- 12/31/18
Polaris Venture Partners 3,148,355 4.43 3,148,355 12/31/18
Palo Alto Investors LP 3,013,793 4.24 -- 6/30/19
The Vanguard Group, Inc. 1,710,492 2.41 1,300 6/30/19
Morgan Stanley & Co. LLC 1,163,457 1.64 -154 6/30/19

Top Holders: Mutual Funds

Fund Shares Held % O/S Share Change Filing Date
Vanguard Total Stock Market Index Fund 937,766 1.32 -- 8/31/19
Vanguard Extended Market Index Fund 661,531 0.93 -- 8/31/19
Royce Value Trust 571,275 0.80 252,089 3/31/19
Bridgeway Ultra-Small Company Market Fund 460,000 0.65 -- 6/30/19
iShares Core S&P Total U.S. Stock Market ETF 135,990 0.19 2,500 9/30/19
VALIC Co I Small Cap Fund 115,025 0.16 -- 8/31/19
Vanguard Institutional Total Stock Market Index Fund 114,589 0.16 -- 8/31/19
Fidelity Extended Market Index Fund 100,515 0.14 -- 8/31/19
Schwab Total Stock Market Index Fund 39,406 0.06 -- 8/31/19
Vanguard Balanced Index Fund 32,384 0.05 -- 8/31/19

* Insider values reflect direct beneficial ownership.

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